IN VITRO BIOEQUIVALENCE PROFILE OF PENICILLIN V TABLETS MARKETED IN KISANGANI, DEMOCRATIC REPUBLIC OF THE CONGO: ASSAY AND DISSOLUTION KINETICS OF GENERIC 250 MG AND ORIGINATOR 600 MG

In vitro bioequivalence profile of Penicillin V tablets marketed in Kisangani, Democratic Republic of the Congo: Assay and dissolution kinetics of generic 250 mg and originator 600 mg

Introduction Phenoxymethylpenicillin is commonly presented in various generic forms and rarely as proprietary brands.Given the prevalence of copyright products and the increased use of generic drugs in sub-Saharan Africa, ensuring drug quality is critical to meet legal requirements for bioequivalence and interchangeable dispensation.Purpose The pur

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ERICA: smoking prevalence in Brazilian adolescents

ABSTRACT OBJECTIVE To estimate the prevalences of tobacco use, tobacco experimentation, and frequent smoking among Brazilian adolescents.METHODS We evaluated participants of the cross-sectional, nation-wide, school-based Study of Cardiovascular Risks in Adolescents (ERICA), which included 12- to 17-year-old adolescents from municipalities of over 1

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Differences in spatio-temporal behavior of zebrafish in the open tank paradigm after a short-period confinement into dark and bright environments.

The open tank paradigm, also known as novel tank diving test, is a protocol used to evaluate the zebrafish behavior.Several characteristics have been described for this species, including scototaxis, which is the natural preference for dark environments in detriment of bright ones.However, there is no evidence regarding the influence of "natural st

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“Words Matter”

Language is a way to behave and influence our environment.A good example of the importance of what we say is what we are experiencing during the current pandemic: instead of staying united more than ever and thinking that we are in this together, the words we use are actually keeping Cases us apart because all they convey is violence, incitement to

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Thermodynamics of Small Magnetic Particles

In the present paper, we discuss the interpretation of some of the results of the thermodynamics in the case of very small systems.Most of the usual statistical physics is done for systems with a huge number of elements in what is called the thermodynamic limit, but not all of the approximations done for those conditions can be extended to all prop

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